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|  | A. David Baker
Organic Chemistry
Remsen, Room 117F
Phone: 718-997-4219
arthur.baker@qc.cuny.edu
Personal Home Page
I was active for many years (1960 - 1980) in ultraviolet and x-ray photoelectron spectroscopy. This work resulted in the publication of numerous papers in journals. In addition I co-authored two books, wrote chapters, review articles, and with my graduate students wrote the "Fundamental Review Feature" on these techniques for Analytical Chemistry during the period 1976-1980. More recently I have become interested in the chemistry of organic nitrogen compounds - nitrones, imines, N-oxides, pyridines and related heterocycles. One area of interest is the use of polypyridines and phenanthroline derivatives as ligands in metal complexes that can interact selectively with DNA. This work has resulted in several publications, is ongoing, and has expanded to include novel synthetic routes to various types of nitrogen-containing heterocycles. More recently we have embarked on the synthesis and study of quaternized quinolines as inhibitors of protein kinase C, with a view to developing new therapeutic agents. |  | |
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| | Yu Chen
Organic Chemistry
Remsen, Room 206F
Phone: 718-997-4132
yu.chen1@qc.cuny.edu
Personal Home Page
Dr. Chen’s research interest includes the topics of late-transition-metal catalysis, asymmetric synthesis and catalysis, and heterocyclic chemistry. The late-transition-metal catalysis topic plays a significant role in Chen research group. His group is particularly interested in group 9 to 11 transition metals, especially Rh, Pd, Pt and Au. Developing new efficient chemical transformations using these late-transition-metal catalysts is currently one of the group’s major objectives. The late-transition-metal catalyzed asymmetric synthesis is another important research topic in Chen group. The group focuses on designing and preparing new ligands with axial chirality or facial chirality for efficient and highly stereoselective chemical reactions catalyzed by late-transition-metals. The synthetic methodologies developed in Chen group will be employed as the key steps in the synthesis of biologically interesting and pharmaceutically important molecules. | | |
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| | Robert Engel
Remsen, Room 206F
Phone: 718-997-4106
robert_engel@qc.edu
Personal Home Page
In addition to our continuing interest in organophosphorus chemistry (syntheses and mechanisms), for several years a major effort of our laboratory has been concerned with the design and syntheses of polycationic organic salts of several topological types including: dendrimers, strings, combs and rings. Most recently, we have been concerned with the conversion of such salts into ionic liquids, and their attachment to surfaces to generate antimicrobial surfaces. Several general topological categories of polycations are under investigation. | | |
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| | Sanjai Kumar
Bioorganic & medicinal chemistry
Remsen, Room 117C
Phone: 718-997-4120
sanjai.kumar@qc.cuny.edu
Personal Home Page
Design, synthesis and evaluation of tight-binding inhibitors of clinically important enzyme targets using a combination of rational and combinatorial approaches, enzyme kinetics and molecular modeling. | | |
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Chair: Wilma Saffran
Dept. Office: Remsen 206
Phone: 718-997-4100, 4482 or 4191
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