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|  | A. David Baker
Organic Chemistry
Remsen, Room 117F
Phone: 718-997-4219
arthur.baker@qc.cuny.edu
Personal Home Page
I was active for many years (1960 - 1980) in ultraviolet and x-ray photoelectron spectroscopy. This work resulted in the publication of numerous papers in journals. In addition I co-authored two books, wrote chapters, review articles, and with my graduate students wrote the "Fundamental Review Feature" on these techniques for Analytical Chemistry during the period 1976-1980. More recently I have become interested in the chemistry of organic nitrogen compounds - nitrones, imines, N-oxides, pyridines and related heterocycles. One area of interest is the use of polypyridines and phenanthroline derivatives as ligands in metal complexes that can interact selectively with DNA. This work has resulted in several publications, is ongoing, and has expanded to include novel synthetic routes to various types of nitrogen-containing heterocycles. More recently we have embarked on the synthesis and study of quaternized quinolines as inhibitors of protein kinase C, with a view to developing new therapeutic agents. |  | |
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| | Yu Chen
Organic Chemistry
Remsen, Room 206F
Phone: 718-997-4132
yu.chen1@qc.cuny.edu
Personal Home Page
Dr. Chen’s research interest includes the topics of late-transition-metal catalysis, asymmetric synthesis and catalysis, and heterocyclic chemistry. The late-transition-metal catalysis topic plays a significant role in Chen research group. His group is particularly interested in group 9 to 11 transition metals, especially Rh, Pd, Pt and Au. Developing new efficient chemical transformations using these late-transition-metal catalysts is currently one of the group’s major objectives. The late-transition-metal catalyzed asymmetric synthesis is another important research topic in Chen group. The group focuses on designing and preparing new ligands with axial chirality or facial chirality for efficient and highly stereoselective chemical reactions catalyzed by late-transition-metals. The synthetic methodologies developed in Chen group will be employed as the key steps in the synthesis of biologically interesting and pharmaceutically important molecules. | | |
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| | Robert Engel
Remsen, Room 206F
Phone: 718-997-4106
robert_engel@qc.edu
Personal Home Page
In addition to our continuing interest in organophosphorus chemistry (syntheses and mechanisms), for several years a major effort of our laboratory has been concerned with the design and syntheses of polycationic organic salts of several topological types including: dendrimers, strings, combs and rings. Most recently, we have been concerned with the conversion of such salts into ionic liquids, and their attachment to surfaces to generate antimicrobial surfaces. Several general topological categories of polycations are under investigation. | | |
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| | Cherice M. Evans
Physical Chemistry
Remsen, Room 206G
Phone: 718-997-4216
cherice.evans@qc.cuny.edu
Personal Home Page
Research interests -- experimental physical chemistry: molecular and atomic spectroscopy, field ionization and photoabsorption of molecular Rydberg states in dense gases and simple fluids, molecular Rydberg-Rydberg transitions, electric field effects on molecular Rydberg states, the effects of rare-gas clusters on molecular Rydberg states, oscillatory absorption and fluorescence in gas-phase and liquid-phase chemical systems, Turing pattern formation in liquid-phase chemical reactions | | |
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| | Seogjoo (Suggy) Jang
Theoretical and Computational Chemistry -Physical Chemistry, Photonics, and Nanoscience
Remsen, Room 119C
Phone: 718-997-4110
seogjoo.jang@qc.cuny.edu
Personal Home Page
Jang’s expertise is in the area of condensed phase quantum dynamical molecular processes. He has worked on path integral simulation, theories of energy/electron transfer, and development of new quantum master equations. His main focus at present is combining these approaches for reliable theoretical description of energy and charge flow dynamics in photosynthetic pigment-protein complexes and in various conjugated organic molecules used for plastic solar cells. | | |
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| | Sanjai Kumar
Bioorganic & medicinal chemistry
Remsen, Room 117C
Phone: 718-997-4120
sanjai.kumar@qc.cuny.edu
Personal Home Page
Design, synthesis and evaluation of tight-binding inhibitors of clinically important enzyme targets using a combination of rational and combinatorial approaches, enzyme kinetics and molecular modeling. | | |
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| | Jianbo Liu
Physical & Analytical Chemistry, and Nanotechnology
Science Building, Room B312
Phone: 718-997-3271
Jianbo.Liu@qc.cuny.edu
Personal Home Page
Our research focuses on using mass spectrometry and ion-molecule reaction techniques to probe biologically relevant processes in a spectrum of systems ranging from isolated biomolecules and biomolecular ions, through micelles and aerosol droplets of biomolecules, to biomolecule solution. <br> <br>We are also interested in discovering and developing new analytical approaches. In addition, we have related interests in computational chemistry (e.g. quasi-classical direct dynamics trajectory simulations) and nano-materials. | | |
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| | Glendon Dale McLachlan
Biochemistry
Remsen, Room 206D
Phone: 718-997-4185
glendon.mclachlan@qc.cuny.edu
Personal Home Page
The research in my lab investigates the relationship between the 3D structures of proteins and how a sampled conformation imparts function. High resolution NMR spectroscopy and spectroscopic methods such as CD, UV-Vis and Trp Fluorescence will be used to shed light on the structural perturbations of proteins in distinct solvents. We are investigating the conformational transitions and dynamics of spider silk proteins in conditions that mimetics the natural processing. | | |
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| | Susan A. Rotenberg
Biochemistry
Remsen, Room 117B
Phone: 718-997-4133
Susan.Rotenberg@qc.cuny.edu
Personal Home Page
Protein kinase C (PKC) is a Ca2+ and phospholipid-dependent protein kinase that is a vital component in various signaling pathways that govern proliferation, differentiation, and cell movement. In malignant cells, PKC promotes unregulated cellular growth and metastasis, as evidenced by 1) its role as the cellular receptor for tumor promoters, 2) its elevated levels of expression in certain tumors, and 3) disturbances in proliferation, migration, and reduction-oxidation processes of cells genetically engineered to overproduce PKC | | |
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| | Uri Samuni
Biophysics, Biochemistry, Physical Chemistry, Bio-nanotechnology, Biophotonics
Remsen, Room 26A
Phone: 718-997-4223
Uri.Samuni@qc.cuny.edu
Personal Home Page
Prof. Uri Samuni has a doctorate in Physical Chemistry from the Hebrew University of Jerusalem, Israel, and postdoctoral training at the Keck Biomolecular Laser Research Center, Albert Einstein College of Medicine. Our research is interdisciplinary in nature involving physical chemistry, biophysics, photonics and nanophotonics. The main objective of our research is combining spectroscopy, specifically, resonance Raman and surface enhanced Raman spectroscopy (SERS), sol-gel encapsulation of proteins and nanoparticles. In sol-gel encapsulation, proteins are embedded in the inert and optically transparent sol-gel matrix and yet remain functionally active. This constitutes a unique platform for the study of protein conformational dynamics and the characterization of non-equilibrium conformations as they relate to protein function. Moreover, depending on the preparative conditions, this novel photonic material lends itself to a large range of applications such as biosensors and sol-gel based nanoparticles and their biomedical applications. | | |
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| | Gopal Subramaniam
NMR, Chemistry Education
Remsen, Room 206C
Phone: 718-997-4123
Personal Home Page
As a facility director for NMR, we involve ourselves with small molecule as well as large molecule structural problems. We are also part of a working group in science education and in particular, I am involved in directing the chemistry education majors to become excellent high school teachers | | |
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